|Tel :||01904 431402||Bioquote Limited|
The Raylor Centre
York, YO10 3DW
|Fax :||01904 431409|
|Int Tel :||00 44 1904 431402|
|Int Fax :||00 44 1904 431409|
Shipping: Cold Gel Packs
The S-HyNic (succinimidyl-6-hydrazino-nicotinamide) heterobifunctional crosslinker is fundamental to Solulink’s proprietary linker technology. Sulfo-S-HyNic is a water soluble analog of S-HyNic. The S-HyNic analog reacts with primary amines on proteins (amino group of lysine) or amino-modified oligonucleotides or surfaces, introducing a HyNic (6-hydrazinonicotinamide) linker that forms stable covalent conjugates with biomolecules possessing 4FB (4-formylbenzamide) incorporated linkers. Sulfo-S-HyNic is recommended for incorporating HyNic linkers on amino-surfaces or biomolecules. This linker is particularly useful for biomolecules or surfaces that are sensitive to organic solvents such as DMF or DMSO.
Solulink’s proprietary linker technology is based on the use of two complementary heterobifunctional linkers:
The result is two biomolecules conjugated through a UV-traceable and stable bond (bis-arylhydrazone) with measurable absorbance at 354 nm. Thus any two proteins, regardless of molecular weight, can be efficiently conjugated.
Solulink Advantages :
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