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Ko 143

Manufacturer: ApexBio
Shipping: Standard

Description : Ko 143 is potent and selective inhibitor of breast cancer resistance protein multidrug transporter (BCRP) with an EC90 value of 26 nM.

Targets : BCRP

IC50 : 26 nM (EC90)

Chemical Properties :

Cas No. : 461054-93-3

SDF : Download SDF

Synonyms : Ko-143;Ko143

Chemical Name : tert-butyl 3-((3R,6S,12aR)-6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino[1\',2\':1,6]pyrido[3,4-b]indol-3-yl)propanoate

Canonical SMILES : O=C1N2[C@@H](CC(C)C)C(NC3=C4C=CC(OC)=C3)=C4C[C@@H]2C(N[C@@H]1CCC(OC(C)(C)C)=O)=O

Formula : C26H35N3O5

M.Wt : 469.59

Solubility : Soluble in DMSO > 10 mM

Storage : Store at -20C

General tips : For obtaining a higher solubility , please warm the tube at 37C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20C for several months.

Shipping Conditions : Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

SizeCatalogue noPrice 
5mg size A3533 £102.00/€142.80
10mg size A3533-10 £164.00/€229.60
25mg size A3533-25 £359.00/€502.60
100mg size A3533-100 £1,234.00/€1,727.60

All prices shown are exlusive of VAT.