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Anti-Human Keratinocyte Transglutaminase Mouse MAb

Manufacturer: Biomedical Technologies Inc
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Anti-Human Keratinocyte Transglutaminase Mouse MAb

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The BTI Human Keratinocyte Transglutaminase MAb recognizes transglutaminase type 1 which is expressed during the differentiation of epidermis and stratified squamous epithelia.  This MAb has been used for immunohistochemical localization on frozen tissues or formaldehyde (2%) fixed tissues and cells from human, hamster, monkey, rabbit and rat sources (paraffin-embedded sections do not stain properly).  The BTI Transglutaminase MAb can be used in a modified elisa for the detection of type 1 transglutaminase expression in response to retinoids. This IgG2a antibody is purified via protein A sepharose.  A complete protocol is included with the MAb, including methods for analyzing tissue sections and cultured cells.

References

1.  Phillips, M.A; Stewart, B.E; Qin, Q; Chakravarty, R; Floyd, E; Jetten, A.M; and Rice, R.H. (1990) Primary Structure of Keratinocyte Transglutaminase. Proc. Natl. Acad. Sci. 87:  9333-9337.

2.  Schmidt, R;  Michel, S;  Shroot, B; and U. Reichert. (1988) Transglutaminase in normal and transformed human keratinocytes in culture. J. Invest. Dermatol. 90:  475-479.

3.  Michel, S; Courseaux, A; Miguel, C; Bernardon, J.M; Schmidt, R; Shroot, B;  Thacher, S.M; and U. Reichert (l991) Determination of retinoid activity by an   enzyme-linked immunosorbent assay. Anal. Biochem. 192:  232-236.

4.  Huber, M; Rettler, I; Bernasconi, K; Frenk, E; Lavrijsen, S; Ponec, M; Bon, A; Lautenschlager, D;  Schorderet, D; and Hohl, D. (1995) Mutations of Keratinocyte Transglutaminase in Lamellar Ichthyosis.  Science. 267:  525-527.

anti-Human Keratinocyte Transglutaminase, Mouse MAb
Catalog No:  BT-621
Quantity:  0.5ml (100 sections)

FOR RESEARCH USE ONLY.  NOT FOR USE IN HUMANS OR AS AN IN-VITRO DIAGNOSTIC.

SizeCatalogue noPrice 
0.5ml size BT-621 £335.00/€469.00
Qty:

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